The Asante Kotoko team have left Accra for their second leg match of the CAF Champions League against Sony Nguema.
A 30-man squad made up of 18 players, seven technical team members and five officials made up the travelling party on Wednesday afternoon.
The team will make a brief stop in Lome, Togo before arriving in the Equatorial Guinean capital by evening.
Kotoko are all but assured of progression with a comfortable 7-0 lead going into the second leg.
The Ghanaian champions look to make a significant impact upon their return to Africa after a four-year absence.