Japan are without influential midfielder Aoyama Toshihiro for the Kirin Challenge Cup friendly against Ghana on Tuesday due to illness.
The Sanfrecce Hiroshima player was forced to leave the Japan squad and return home to Hiroshima on Saturday morning.
Aoyama complained of a pain in the stomach on Friday night after coming off the bench to play in Japan’s 3-0 win over Guatemala at Osaka Nagai Stadium.
Japan boss Alberto Zaccheroni will not call up a replacement for the midfielder.
The match will be played at Yokohama International Stadium.