It’s a crunch game for the Black Stars, who lost 2-1 to Senegal in their opener on Monday and must record a positive result to stay in quarterfinal contention.
Ghana’s starting line-up:
Razak Brimah, Harrison Afful, Baba Rahman, Daniel Amartey, Jonathan Mensah, Afriyie Acquah, Christian Atsu, Emmanuel Agyemang Badu, Asamoah Gyan, Jordan Ayew, Andre Ayew.
As for the Fennec Foxes, their 3-1 win over South Africa means they are sitting pretty at the top of the group. However, they will definitely not be taking the challenge of Ghana lightly.
The big team news for Ghana is the return to the line-up of Asamoah Gyan, as well as a return to a more traditional 4-4-2 formation from coach Avram Grant.
Christian Gourcuff has made three changes to the XI that started against SA, with Madjid Bougherra replacing Rafik Halliche in defence, while Ishak Belfodil and Saphir Taider replace Riyad Mahrez and Islam Slimani.
1'The match is underway!
2'Ghana wear their traditional all-white, Algeria are in all-green.
4'Ghoulam goes for goal from the set piece, but it drifts wide of the target.
5'Brahimi wins a free kick in a useful attacking position for Algeria.
6'This is good stuff from Algeria - lots of quick passing, lots of movement off the ball. Ghana are struggling to win any possession.
7'It's all Algeria in the early minutes, just as it was when they played South Africa.
8'The Fennec Foxes almost succeed in getting Belfodil in behind the defence.
9'Ghoulam goes for goal from the set piece, but it drifts wide of the target
Gyan tumbles under a challenge from Medjani but there's no free kick forthcoming. Should be quite the battle between those two...
11'Past the 10 minute mark now. Still goalless, but Algeria have definitely looked the better team at this early stage.
Belfodil does brilliantly to beat one defender's challenge but then carelessly gives the ball away while looking for a teammate.
12'Belfodil is flagged offside, ending a promising move from Algeria.
14'Brahimi delivers a ball into the Ghana box, headed clear by Atsu.
16'Gyan tumbles under a challenge from Medjani but there's no free kick forthcoming. Should be quite the battle between those two...
Brahimi is chopped down by Acquah in midfield, with the Ghanaian lucky not to be booked.
17'Afful with a chance to cross from the right, but he fails to beat the first defender.
18'Taider with a pull-back from the right by-line, Bentaleb with the shot... but he's scuffed it wide of the far post!
19'Brahimi wins another free kick inside the Ghanaian half. He's a difficult man to dispossess.
20'Belfodil does brilliantly to beat one defender's challenge but then carelessly gives the ball away while looking for a teammate.
21'Belfodil is flagged offside, ending a promising move from Algeria
Atsu with a cross from a corner kick, but it's well defended by the North Africans. 
22'Afriyie Acquah (Ghana) is cautioned. 
23'Past the midway point of the first half, still goalless in Mongomo.
24'Brahimi is chopped down by Acquah in midfield, with the Ghanaian lucky not to be booked.
25'Afful with a chance to cross from the right, but he fails to beat the first defender.
There's some bite in this game now... let's just hope we see some scoring chances in the near future.
31'No cards from the referee, just a talking-to.
30'There's an altercation between Agyemang-Badu and Belfodil that could see some cards produced...
28'Atsu with a cross from a corner kick, but it's well defended by the North Africans.
29'Belfodil looks to play a cute ball into the path of Brahimi, but Ghana just about do enough to stymie the Algerian attack.
30'Afful with a good cross from the right, Bougherra makes a great headed clearance ahead of Gyan.
31'Less than 10 minutes left of the first half. Algeria will probably be the happier of the two teams with proceedings thus far.
32'Neither coach looks particularly happy on the sidelines. It's not been a good match given the quality both of these sides possess.
34'There's some bite in this game now... let's just hope we see some scoring chances in the near future.
35'No cards from the referee, just a talking-to.
36There's an altercation between Agyemang-Badu and Belfodil that could see some cards produced.
Atsu with another corner kick, Medjani heads clear from the middle of the box.Â
42'The game is opening up a little more in the dying minutes of the first half...
43'Belfodil looks to play a cute ball into the path of Brahimi, but Ghana just about do enough to stymie the Algerian attack
Atsu with another corner kick, Medjani heads clear from the middle of the box.Â
44'The game is opening up a little more in the dying minutes of the first half.
Madjid Bougherra (Algeria) is cautioned.Â
45'Atsu looks to turn in the box, Gyan gets a shot away... but it's blocked by an Algerian defender. Definitely Ghana's best attacking moment thus far.
43'Atsu with another corner kick, Medjani heads clear from the middle of the box.Â
45'The game is opening up a little more in the dying minutes of the first half.
The second half is underway
Jordan Ayew break free down the left, cuts back inside and looks to shoot, but his effort is half blocked and easily collected by the 'keeper.
Mandi with a deep cross from the right, but Braimah makes a good catch.
50'Andre Ayew receives some treatment after having his foot trod on, but he's fine to play on.Mandi with a crucial header back to his goalkeeper as Ghana threaten again.
Mandi with a crucial header back to his goalkeeper as Ghana threaten again
Ghana: Mubarak Wakaso replaces Afriyie Acquah 
Algeria: Islam Slimani replaces Ishak BelfodilÂ
t's been Ghana's half so far, with the West Africans looking much livelier in attack.
Brahimi looks to chip a ball into the box but it ends up safely in the hands of the Ghana goalkeeper.
Andre Ayew fires a ball toward his brother in the box, whose back-heel almost finds the top corner!
Gyan through on goal but he's flagged offside. TV replays suggest it was probably a wrong call...
Algeria on the counter, Bentaleb shoots from the left of the box... just wide of the far post!
Algeria on the counter, Bentaleb shoots from the left of the box... just wide of the far post!
Wakaso crosses from a corner, headed clear by Bougherra.Â
Another Ghana corner, this time it passes through the box untouched.Â
Algeria: Riyad Mahrez replaces Medhi LacenÂ
Andre Ayew with a free header in the box, but he puts it over! The cross from Atsu was just a touch too high for him...
Nabil Bentaleb (Algeria) is cautioned.Â
72'Andre Ayew with a free header in the box, but he puts it over! The cross from Atsu was just a touch too high for him...
Jordan Ayew chips a ball into the box looking for Gyan, but it's straight into the hands of Mbolhi.
73'Nabil Bentaleb (Algeria) is cautioned.
Jordan Ayew chips a ball into the box looking for Gyan, but it's straight into the hands of Mbolhi.
73'Nabil Bentaleb (Algeria) is cautioned.
Ghana: Mahatma Otoo replaces Jordan AyewÂ
Ghana: Mahatma Otoo replaces Jordan AyewÂ
76'Mahrez with a left-footed shot from a tight angle... well wide of the goal.
Gyan shoots from the set piece... high and wide, really disappointing.
80'Free kick for Ghana from a potential shooting position...
Bougherra has to tidy up a poor defensive header that almost allows Gyan in on goal.
84'Ghana: Asante Solomon replaces Andre AyewÂ
Algeria: Foued Kadir replaces Yacine BrahimiÂ
85'Bougherra has to tidy up a poor defensive header that almost allows Gyan in on goal.
Great defensive work by Mandi to quell the threat of Otoo.
88'It's looking like a goalless stalemate, certainly a better result for Algeria than Ghana.
A cross from Afful causes some consternation in the Algeria box, but Gyan can't quite get onto it.
89'Great defensive work by Mandi to quell the threat of Otoo.
A cross from Afful causes some consternation in the Algeria box, but Gyan can't quite get onto it.
89'Great defensive work by Mandi to quell the threat of Otoo.
90 + 2'Asamoah Gyan (Ghana) scores! 